Biobank japan release of disease traits

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August undefined, 2024

WebJun 8, 2024 · The 42 diseases encompassed a wide range of disease categories: 13 neoplastic diseases, five cardiovascular diseases, four … WebOct 25, 2024 · Researchers from Osaka University address inequities in genomic research by analyzing data for over 200 health-related traits and diseases in an Asian population …

Overview of BioBank Japan follow-up data in 32 diseases

WebMar 29, 2024 · Lastly, we identified nine disease traits at least nominally significant in discovery and Bonferroni-significant in replication, categorized as tier 3 results. Several … WebApr 11, 2024 · White blood cell (WBC) counts in peripheral blood are a quantitative trait, and increased or decreased counts are part of stereotypical disease process for AI disorders 13, 14. In general ... great ice wall fairy soul

The association between daytime napping and risk of type 2 …

WebJun 16, 2024 · We present and assess the UK Biobank (UKB) Polygenic Risk Score (PRS) Release, a set of PRSs for 28 diseases and 25 quantitative traits being made available on the individuals in UKB. We also release a benchmarking software tool to enable like-for-like performance evaluation for different PRSs for the same disease or trait. Extensive … WebJan 3, 2024 · MR inference using our gut microbiome M-GWAS summary data and disease GWAS summary statistics from Biobank Japan found that Alistipes, which showed negative effects on blood triglyceride in the 4D ... WebA biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, … floating horizontal wall cabinet

Genome-wide study on 72,298 Korean individuals in Korean biobank …

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WebCurrent genome-wide association studies do not yet capture sufficient diversity in populations and scope of phenotypes. To expand an atlas of genetic associations in non-European populations, we conducted 220 deep-phenotype genome-wide association studies (diseases, biomarkers and medication usage) in BioBank Japan (n = 179,000), by … WebBiobank Japan release of disease traits: 120: ebi-a: Datasets that satisfy minimum requirements imported from the EBI database of complete GWAS summary data: 2,585: … floating homes vancouver bc rentalsWebMar 21, 2024 · Growing evidence suggests that red meat consumption is a risk factor for cardiovascular health, with potential sex disparity. The metabolic mechanisms have not been fully understood. Using the UK Biobank, first we examined the associations of unprocessed red meat and processed meat with ischemic heart disease (IHD) mortality … floating home uk

"WebApr 4, 2024 · Results: In the Japanese genome-wide association study, we identified 10 loci that presented suggestive evidence for the association with the PA risk (P<1.0×10 −6).In the meta-analysis, we identified 5 genome-wide significant loci (1p13, 7p15, 11p15, 12q24, and 13q12; P<5.0×10 −8), including 3 of the suggested loci in the Japanese genome-wide … " - Biobank japan release of disease traits

Biobank japan release of disease traits

Web18 hours ago · Abstract. Reproduction involves a wide range of biological processes, including organ formation and development, neuroendocrine regulation, hormone production, and meiosis and mitosis. Infertility, the failure of reproduction, has become a major issue for human reproductive health and affects up to one in seven couples …

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Web14 Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan. [email protected]. 15 Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan. [email protected]. WebNov 29, 2024 · in a curated set of human diseases and traits using a unique resource of 200,000 individuals with exome sequencing data from the UK Biobank. Methods and Results: We included 199,832 participants with a mean age of 68 at follow-up. Exome-wide gene-based tests were performed for 64 diseases and 23 quantitative traits using a …

WebNational Center for Biotechnology Information WebJun 8, 2024 · Here, we report a genome-wide association study (GWAS) of 42 common diseases in the BioBank Japan Project (BBJ) 15,16 —one of the largest non-European biobanks, consisting of around 200,000 ...

WebApr 15, 2024 · We identified 979 novel genetic loci, pinpointed novel causal variants through fine-mapping, compared the genetic architecture across TWB, Biobank Japan (BBJ) … WebDec 10, 2024 · UK Biobank is a major prospective epidemiological study that is carrying out detailed multimodal brain imaging on 100,000 participants, and includes genetics and ongoing health outcomes. As a step forwards in understanding genetic influence on brain structure and function, in 2024 we published genome-wide associations of 3,144 brain …

WebUpdating SNP heritability results from 4,236 phenotypes in UK Biobank A quick summary of what has changed since the last release.. Insights from estimates of SNP-heritability for >2,000 traits and disorders in UK Biobank We discuss what we have learned so far from the heritability analysis of the UK Biobank phenotypes.

WebFeb 23, 2024 · To expand an atlas of genetic associations in non-European populations, we conducted 220 deep-phenotype genome-wide association studies (diseases, biomarkers and medication usage) in BioBank Japan ... floating home vacation rentals oregonWebBioBank Japan (BBJ) was launched in 2003, establishing a large patient-oriented biobank in order to contribute to the imple- mentation of personalized medicine. great ice storm of 2/22/22WebApr 15, 2024 · Here we report findings from 102,900 individuals across 36 human quantitative traits in the Taiwan Biobank (TWB), a major biobank effort that broadens … floating home vacation rental orlando flWebWe applied PolyPred + to 23 diseases/traits in UK Biobank east Asians using both UK Biobank British and Biobank Japan training data, and observed improvements of +24% versus BOLT-LMM and +12% versus PolyPred. Summary statistics-based analogs of PolyPred and PolyPred + attained similar improvements. floating home vs houseboatWebNov 21, 2024 · Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank J Hum Genet. 2024 Nov 21. doi: 10.1038 ... we conducted a GWAS to identify loci related to multiple kidney-related traits in Japanese individuals. First, to detect loci associated with CKD, eGFR, ... great iconsWebJul 5, 2016 · A biobank is a repository that stores and manages biological samples known as biospecimens for use in research. The Precision Medicine Initiative (PMI) Cohort … floating hookah diving systemWebFeb 23, 2024 · as Biobank Japan (BBJ)8-10 or Taiwan Biobank (TWB)11. By increasing the sample size and demographic ... family disease history information of disease endpoints with TAPE 18. In two types of cancer: gastric ... Genome-wide study on 72,298 Korean individuals in Korean biobank data for 76 traits identifies hundreds of novel loci ... great ice wall