Crystalluria acyclovir
WebApr 1, 2008 · One of the mechanisms for acyclovir-induced nephrotoxicity is acyclovir-induced crystalluria. Prompt attention to urine microscopy examination can help avoid drug-induced nephrotoxicity. WebAcyclovir is a new antiviral drug that acts as a specific inhibitor of herpesvirus DNA polymerase. It shows good in vitro activity against herpes simplex and varicella-zoster viruses. ... The most important adverse effect is crystalluria and elevated serum creatinine related to bolus intravenous administration. Other reported adverse effects ...
Crystalluria acyclovir
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WebOf 19 children treated with high-dose intravenous acyclovir, 7, all of whom had encephalitis, also had a restricted fluid intake. Of these, 3 experienced nonoliguric renal insufficiency (plasma creatinine up to 176, 250 and 351 μmol/l, respectively) which resolved within 1 week of discontinuing acyclovir. Renal function was stable in the remaining 4 patients in … WebMar 6, 2024 · Applies to acyclovir: buccal tablet, compounding powder, intravenous powder for injection, intravenous solution, oral capsule, oral suspension, oral tablet. General The …
Webstatuses. It appears that our patient was affected by acyclovir-mediated nephrotoxicity that manifested on biopsy by acute tubular necrosis and the absence of crystalluria or crystal deposition. Intravenous acyclovir treatment can therefore produce rapidly progressive acute neurologic and renal toxicity that is usually reversible. The pathologic WebAcyclovir crystalluria is considered a rare adverse effect which is more commonly described if there is intravenous administration. However, it may also be associated with oral administration [9]. It is more common in immunosuppressed patients, probably due …
WebAcyclovir crystalluria is a rare condition which is generally described in immunosuppressed adult patients. It can lead to transient renal failure, and therefore it shall be taken into … WebMay 6, 2024 · Primidone crystalluria following overdose a report of a case and an analysis of the literature. Med Toxicol Adverse Drug Exp. Sep-Oct 1987;2 (5):383-7. PMID: 3312932. VanHeijst ANP, Dejong W, Seldenrijk R, Vankijk A. Coma and crystalluria: a massive primidone intoxication treated with haemoperfusion. J Toxicol Clin Toxicol. 1983 Jun;20 …
WebApr 8, 2024 · INTRODUCTION. Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction. Crystal-induced AKI … simply scaffoldingWebAcyclovir is filtered by glomeruli and secreted in renal tubules producing high tubular concentrations. It is relatively insoluble in urine. Intra-tubular crystals obstruct the nephron leading to acute renal failure. Crystalluria usually … ray\u0027s trash recycling scheduleWebJan 1, 2016 · Acyclovir is a highly active antiviral drug that acts against the herpes simplex virus (HSV). Among its secondary effects, we can observe rare cases of crystalluria, which can be associated or not ... ray\\u0027s trash schedule zionsvilleWebFor decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir … ray\u0027s trash service brownsburgWebSep 14, 2024 · Acyclovir crystals in the urine of a 28-year-old woman are described. The patient received intravenous acyclovir for herpes encephalitis. The crystalluria was accompanied by impairment of the ... ray\u0027s trash westfield indianaWebThe only official Kaplan Lecture Notes for USMLE Step 1 cover the comprehensive information you need to ace the exam and match into the residency of your choice. * Up-to-date: Updated annually by Kaplan’s all-star faculty * Integrated: Packed with clinical correlations and bridges between disciplines * Learner-efficient: Organized in outline … ray\\u0027s trash service scheduleWebJun 1, 1988 · One patient was rechallenged with low-dose intravenous acyclovir and the four patients later received oral acyclovir, all without adverse effect. The combined data from these patients support crystalluria and obstructive nephropathy as a mechanism of acyclovir-induced renal failure in humans. ray\\u0027s trash schedule