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WebMay 11, 2024 · These IND-enabling nonclinical studies are promising and support future clinical development. Our team continues to work towards submission of INDs for AK … WebSearch Orphan Drug Designations and Approvals. A recombinant adeno-associated viral (AAV) vector encoding the human otoferlin (hOTOF) gene. The sponsor address listed is the last reported by the sponsor to OOPD. *Exclusivity Protected Indications are shown for approvals from Jan. 1, 2013, to the present. flight clark to cebu
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WebSep 14, 2024 · The FDA has cleared an investigational new drug (IND) application for Akouos’ AK-OTOF, an investigational dual adeno-associated viral (AAV) vector-based gene therapy intended for the treatment of otoferlin gene (OTOF)-mediated hearing loss, clearing the way for a clinical trial to begin. 1AK-OTOF delivers transgenes encoding OTOF, the … WebShare your videos with friends, family, and the world WebFeb 25, 2024 · Updated on February 25, 2024. Higher-order thinking skills (HOTS) is a concept popular in American education. It distinguishes critical thinking skills from low-order learning outcomes, such as those attained by rote memorization. HOTS include synthesizing, analyzing, reasoning, comprehending, application, and evaluation. flight classes army