Webb28 mars 2024 · Small G proteins in the superfamily have a common 20 K molecular weight catalytic (GTPase) domain with 5 alpha helices, 6 beta strands, and connecting loops. The small G proteins are "active" in the GTP-bound form. Hydrolysis of GTP to GDP causes the protein to become inactive. Figure 28.5. 1 shows the domain structures of small G … Webb23 jan. 2024 · G-protein-signaling modulator 2 (GPSM2) is an important factor that regulates the localization and mitotic spindle pole orientation of cells. 13 Fukukawa et al …
Small G Proteins Dexras1 and RHES and Their Role in ... - Hindawi
WebbThe function of small G protein signalling modulators (SGSM1/2/3) in cancer remains unknown. Our findings demonstrated that SGSM2 is a plasma membrane protein that … WebbG-protein-signaling modulator 1 (GPSM1), an accessory protein which activates heterotrimeric G-protein signaling, exhibits a genetic association with type 2 diabetes. optia ltd. inc
28.5: Small G proteins, GAPs and GEFs - Biology LibreTexts
WebbSgsm2 small G protein signaling modulator 2 [ (house mouse)] Gene ID: 97761, updated on 8-Nov-2024. Summary. Enables GTPase activator activity. Predicted to be involved in … Webb20 apr. 2010 · Colocalizes with NUMA1 to mitotic spindle poles ( PubMed: 11781568, PubMed: 21816348 ). Localized at the central and lateral cell cortex regions in a RanGTP … Webb23 jan. 2024 · G-protein-signaling modulator 2 (GPSM2) is an important factor that regulates the localization and mitotic spindle pole orientation of cells. 13 Fukukawa et al have shown that GPSM2 is upregulated in breast cancer tissues and plays an essential role in cell division. 14 In our previous study, we demonstrated that GPSM2 is overexpressed … optia machine